Retatrutide
research use only; not for human
Property
Value
Product Name
Retatrutide
Cas No.
2381089-83-2
Purity
95.00%
Properties State
White Powder
Molecular Weight
4731.33
Molecular Formula
C221H342N46O68
Elemental Analysis
C, 56.05; H, 7.23; N, 13.61; O, 22.99;
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Description
Retatrutide is an investigational single molecule that activates the body's receptors for three hormones — glucagon, glucose-dependent insulinotropic polypeptide (GIP), and glucagon-like peptide-1 (GLP-1), and is being studied for the treatment of obesity.
Mechanism of Action
Retatrutide (LY3437943) is a triple agonist peptide of the glucagon receptor (GCGR), glucosedependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1 R), Retatrutide inhibits for human GCGR, GIPR, and GLP-1 R with EC5O values of 5.79, 0.0643 and 0.775 nM, respectively. Retatrutide can be used for the research of obesity